Research Progress on Pathogenesis and Treatment Targets of Chloasma Based on Network Pharmacology

Abstract

In recent years, with the deepening research on biological networks, drug action targets and their relationships, it has been found that many chemical drugs with single chemical components and clear targets have multi-target microscopic action mechanisms from the perspective of biological regulatory networks. Therefore, the concept of network pharmacology has been put forward and has become one of the important methods for studying the action mechanisms of traditional Chinese medicine compounds. Neuro-endocrine-immune network (NEI) is an important system for the overall maintenance of the body's steady state. At present, the research on the mechanism of neuro- endocrine-immune network is also one of the frontier fields of modern medicine. Under the guidance of network pharmacology, this paper analyzes the pathogenesis of chloasma from the perspective of NEI by using modern medical technology, summarizes the channels and related targets for drug treatment of chloasma, provides new ideas for the treatment of chloasma, and also provides reference for exploring the significance and value of network pharmacology theory in the research of the mechanism of action of traditional Chinese medicine and drug targets.