Study on the Pathogenesis and Therapeutic Targets of Vitiligo Based on Network Pharmacology

Abstract

Vitiligo is a skin disease characterized by acquired depigmentation, which is mainly manifested as white patches on the skin, mucosa or hair, affecting patients' mental health and quality of life. The pathogenesis of vitiligo is complex, easy to diagnose and difficult to treat. Single target is difficult to cure or control the disease, it is necessary to intervene from different targets. The rise of network pharmacology makes it possible to find the target of vitiligo from different levels. In this paper, the pathogenesis of vitiligo was summarized from different perspectives with neuroendocrine immunity as the main line, and the potential targets of vitiligo were screened and discussed under the guidance of network pharmacology, so as to provide new ideas for the basic research and treatment of vitiligo.