Experimental Investigation on Cell Electroporation under Different Applied Conditions

Abstract

Cell electroporation referring to the formation of micro pores on cell membrane caused by externally applied electrical field is a membrane phenomenon which involves fundamental behavior of cell and artificial bilayer membrane, and increasingly attracts consideration in biology, biotechnology and medicine. To improve cell viability and transfection rate, we systemically studied on electroporation under different conditions: (1) ultrasound with different power and frequency, (2) magnetic fields in electroporation, (3) value of pH during electroporation.